How to use them
Use them in the same routine at night. Apply Alpha Arbutin first, then Hydroquinone, moving from thinnest to thickest texture.
- 1CleanseGentle cleanser, pat dry
- 2Alpha Arbutin1% – 2%, wait about 1 minute
- 3Hydroquinone2% – 4% (prescription in India)
- 4Moisturiserseal everything in
What Alpha Arbutin does
A skin-friendly relative of hydroquinone that slows melanin production. It fades dark spots and tanning gradually with very little irritation.
- Typical strength
- 1% – 2%
- When
- AM/PM
- Irritation
- Best for
- Normal, Oily, Combination, Dry And Sensitive skin
Everything that pairs with Alpha Arbutin →
What Hydroquinone does
The strongest topical depigmenting agent, used for melasma and stubborn dark spots. It blocks melanin production, but it must be used in short, supervised courses: long-term use can cause irritation and, rarely, ochronosis (blue-black darkening).
- Typical strength
- 2% – 4% (prescription in India)
- When
- PM
- Irritation
- Best for
- Normal, Oily And Combination skin
Everything that pairs with Hydroquinone →
Trying to choose one? Read Alpha Arbutin vs Hydroquinone: which is better for your skin.
Frequently asked questions
Can I use Alpha Arbutin and Hydroquinone together?
Yes, it is safe. There is no known chemical conflict between Alpha Arbutin and Hydroquinone, and neither makes the other less effective. They share a goal (pigmentation), so together they reinforce each other.
Which goes first, Alpha Arbutin or Hydroquinone?
Apply Alpha Arbutin first, then Hydroquinone. The general rule is thinnest to thickest texture, and lowest pH first.
Should I use Alpha Arbutin in the morning or at night?
Alpha Arbutin: works morning or night. Apply twice daily before heavier serums and creams.
Should I use Hydroquinone in the morning or at night?
Hydroquinone: best at night. Use only under a dermatologist's guidance, typically nightly on the dark patches for up to 3 months, then take a break. Strict daily sunscreen is required or results reverse.
Is Alpha Arbutin with Hydroquinone safe during pregnancy?
Hydroquinone is generally avoided during pregnancy and breastfeeding. Ask your doctor about safer alternatives such as azelaic acid or bakuchiol.