How to use them
Use them in the same routine at night. Apply Alpha Arbutin first, then Tretinoin, moving from thinnest to thickest texture.
- 1CleanseGentle cleanser, pat dry
- 2Alpha Arbutin1% – 2%, wait about 1 minute
- 3Tretinoin0.025% – 0.1% (prescription)
- 4Moisturiserseal everything in
What Alpha Arbutin does
A skin-friendly relative of hydroquinone that slows melanin production. It fades dark spots and tanning gradually with very little irritation.
- Typical strength
- 1% – 2%
- When
- AM/PM
- Irritation
- Best for
- Normal, Oily, Combination, Dry And Sensitive skin
Everything that pairs with Alpha Arbutin →
What Tretinoin does
The prescription-strength retinoid, and the gold standard for acne and photo-ageing, with decades of evidence. It works directly (no conversion needed), so it is stronger and more irritating than retinol or retinal.
- Typical strength
- 0.025% – 0.1% (prescription)
- When
- PM
- Irritation
- Best for
- Oily, Normal And Combination skin
Everything that pairs with Tretinoin →
Trying to choose one? Read Alpha Arbutin vs Tretinoin: which is better for your skin.
Frequently asked questions
Can I use Alpha Arbutin and Tretinoin together?
Yes, it is safe. There is no known chemical conflict between Alpha Arbutin and Tretinoin, and neither makes the other less effective. They share a goal (pigmentation), so together they reinforce each other.
Which goes first, Alpha Arbutin or Tretinoin?
Apply Alpha Arbutin first, then Tretinoin. The general rule is thinnest to thickest texture, and lowest pH first.
Should I use Alpha Arbutin in the morning or at night?
Alpha Arbutin: works morning or night. Apply twice daily before heavier serums and creams.
Should I use Tretinoin in the morning or at night?
Tretinoin: best at night. Use only as prescribed: a pea-sized amount on completely dry skin at night, starting 2–3 nights a week. Expect dryness and a possible purge for 4–8 weeks. Daily SPF is essential.
Is Alpha Arbutin with Tretinoin safe during pregnancy?
Tretinoin is generally avoided during pregnancy and breastfeeding. Ask your doctor about safer alternatives such as azelaic acid or bakuchiol.