Beauty Elixir

Can you use Azelaic Acid with Retinal?

Safe to mix

Yes, it is safe.

There is no known chemical conflict between Azelaic Acid and Retinal, and neither makes the other less effective. They share a goal (acne and pigmentation), so together they reinforce each other.

How to use them

Use them in the same routine at night. Apply Azelaic Acid first, then Retinal, moving from thinnest to thickest texture.

  1. 1
    CleanseGentle cleanser, pat dry
  2. 2
    Azelaic Acid10% – 20%, wait about 1 minute
  3. 3
    Retinal0.05% – 0.2%
  4. 4
    Moisturiserseal everything in

What Azelaic Acid does

A multitasker that treats acne, rosacea redness and pigmentation at the same time. It is widely considered safe in pregnancy, so it is a common swap for retinoids.

Typical strength
10% – 20%
When
AM/PM
Irritation
Best for
Sensitive, Oily, Combination And Normal skin

Everything that pairs with Azelaic Acid →

What Retinal does

Retinaldehyde is one conversion step closer to retinoic acid than retinol, so it works faster than retinol while usually being gentler than tretinoin. It also has a mild antibacterial effect useful for acne.

Typical strength
0.05% – 0.2%
When
PM
Irritation
Best for
Normal, Oily, Combination And Dry skin

Everything that pairs with Retinal →

Trying to choose one? Read Azelaic Acid vs Retinal: which is better for your skin.

Frequently asked questions

Can I use Azelaic Acid and Retinal together?

Yes, it is safe. There is no known chemical conflict between Azelaic Acid and Retinal, and neither makes the other less effective. They share a goal (acne and pigmentation), so together they reinforce each other.

Which goes first, Azelaic Acid or Retinal?

Apply Azelaic Acid first, then Retinal. The general rule is thinnest to thickest texture, and lowest pH first.

Should I use Azelaic Acid in the morning or at night?

Azelaic Acid: works morning or night. Apply once or twice daily. A mild tingle in the first week is normal.

Should I use Retinal in the morning or at night?

Retinal: best at night. Start at 0.05% two or three nights a week and build up slowly. Buffer with moisturiser if you are sensitive, and wear SPF daily.

Is Azelaic Acid with Retinal safe during pregnancy?

Retinal is generally avoided during pregnancy and breastfeeding. Ask your doctor about safer alternatives such as azelaic acid or bakuchiol.

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