Beauty Elixir

Can you use Hyaluronic Acid with Tretinoin?

Great combo

Yes, and they work even better together.

Hyaluronic Acid cushions Tretinoin: it hydrates and supports the barrier while the active does its work. That means less irritation and better results.

How to use them

Use them in the same routine at night. Apply Hyaluronic Acid first, then Tretinoin, moving from thinnest to thickest texture.

  1. 1
    CleanseGentle cleanser, pat dry
  2. 2
    Hyaluronic Acid0.1% – 2%, wait about 1 minute
  3. 3
    Tretinoin0.025% – 0.1% (prescription)
  4. 4
    Moisturiserseal everything in

What Hyaluronic Acid does

A humectant that holds many times its weight in water, plumping skin and smoothing dehydration lines. It pairs well with almost everything and cushions harsher actives.

Typical strength
0.1% – 2%
When
AM/PM
Irritation
Best for
Dry, Normal, Oily, Combination And Sensitive skin

Everything that pairs with Hyaluronic Acid →

What Tretinoin does

The prescription-strength retinoid, and the gold standard for acne and photo-ageing, with decades of evidence. It works directly (no conversion needed), so it is stronger and more irritating than retinol or retinal.

Typical strength
0.025% – 0.1% (prescription)
When
PM
Irritation
Best for
Oily, Normal And Combination skin

Everything that pairs with Tretinoin →

Frequently asked questions

Can I use Hyaluronic Acid and Tretinoin together?

Yes, and they work even better together. Hyaluronic Acid cushions Tretinoin: it hydrates and supports the barrier while the active does its work. That means less irritation and better results.

Which goes first, Hyaluronic Acid or Tretinoin?

Apply Hyaluronic Acid first, then Tretinoin. The general rule is thinnest to thickest texture, and lowest pH first.

Should I use Hyaluronic Acid in the morning or at night?

Hyaluronic Acid: works morning or night. Apply on slightly damp skin and seal with a moisturiser. In very dry air, skipping the seal can leave skin tighter.

Should I use Tretinoin in the morning or at night?

Tretinoin: best at night. Use only as prescribed: a pea-sized amount on completely dry skin at night, starting 2–3 nights a week. Expect dryness and a possible purge for 4–8 weeks. Daily SPF is essential.

Is Hyaluronic Acid with Tretinoin safe during pregnancy?

Tretinoin is generally avoided during pregnancy and breastfeeding. Ask your doctor about safer alternatives such as azelaic acid or bakuchiol.

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