How to use them
Use them in the same routine at night. Apply Tea Tree Oil first, then Tretinoin, moving from thinnest to thickest texture.
- 1CleanseGentle cleanser, pat dry
- 2Tea Tree Oil5% (diluted), wait about 1 minute
- 3Tretinoin0.025% – 0.1% (prescription)
- 4Moisturiserseal everything in
What Tea Tree Oil does
An essential oil with modest evidence against mild acne. It works more slowly than benzoyl peroxide but causes less dryness. Undiluted it can irritate or sensitise skin, so it belongs in a formulated product.
- Typical strength
- 5% (diluted)
- When
- AM/PM
- Irritation
- Best for
- Oily And Combination skin
Everything that pairs with Tea Tree Oil →
What Tretinoin does
The prescription-strength retinoid, and the gold standard for acne and photo-ageing, with decades of evidence. It works directly (no conversion needed), so it is stronger and more irritating than retinol or retinal.
- Typical strength
- 0.025% – 0.1% (prescription)
- When
- PM
- Irritation
- Best for
- Oily, Normal And Combination skin
Everything that pairs with Tretinoin →
Trying to choose one? Read Tea Tree Oil vs Tretinoin: which is better for your skin.
Frequently asked questions
Can I use Tea Tree Oil and Tretinoin together?
Yes, it is safe. There is no known chemical conflict between Tea Tree Oil and Tretinoin, and neither makes the other less effective. They share a goal (acne), so together they reinforce each other.
Which goes first, Tea Tree Oil or Tretinoin?
Apply Tea Tree Oil first, then Tretinoin. The general rule is thinnest to thickest texture, and lowest pH first.
Should I use Tea Tree Oil in the morning or at night?
Tea Tree Oil: works morning or night. Use a product with around 5% tea tree, or dilute it. Never apply the pure oil straight to the face. Patch test first.
Should I use Tretinoin in the morning or at night?
Tretinoin: best at night. Use only as prescribed: a pea-sized amount on completely dry skin at night, starting 2–3 nights a week. Expect dryness and a possible purge for 4–8 weeks. Daily SPF is essential.
Is Tea Tree Oil with Tretinoin safe during pregnancy?
Tretinoin is generally avoided during pregnancy and breastfeeding. Ask your doctor about safer alternatives such as azelaic acid or bakuchiol.