How to use them
Use them in the same routine at night. Apply Tranexamic Acid first, then Tretinoin, moving from thinnest to thickest texture.
- 1CleanseGentle cleanser, pat dry
- 2Tranexamic Acid2% – 5%, wait about 1 minute
- 3Tretinoin0.025% – 0.1% (prescription)
- 4Moisturiserseal everything in
What Tranexamic Acid does
A gentle brightener that interrupts the signals behind melasma, sun spots and post-acne marks, without the irritation of hydroquinone or strong acids.
- Typical strength
- 2% – 5%
- When
- AM/PM
- Irritation
- Best for
- Sensitive, Normal, Oily, Combination And Dry skin
Everything that pairs with Tranexamic Acid →
What Tretinoin does
The prescription-strength retinoid, and the gold standard for acne and photo-ageing, with decades of evidence. It works directly (no conversion needed), so it is stronger and more irritating than retinol or retinal.
- Typical strength
- 0.025% – 0.1% (prescription)
- When
- PM
- Irritation
- Best for
- Oily, Normal And Combination skin
Everything that pairs with Tretinoin →
Trying to choose one? Read Tranexamic Acid vs Tretinoin: which is better for your skin.
Frequently asked questions
Can I use Tranexamic Acid and Tretinoin together?
Yes, it is safe. There is no known chemical conflict between Tranexamic Acid and Tretinoin, and neither makes the other less effective. They share a goal (pigmentation), so together they reinforce each other.
Which goes first, Tranexamic Acid or Tretinoin?
Apply Tranexamic Acid first, then Tretinoin. The general rule is thinnest to thickest texture, and lowest pH first.
Should I use Tranexamic Acid in the morning or at night?
Tranexamic Acid: works morning or night. Use once or twice daily for at least 8–12 weeks. It works best alongside a daily broad-spectrum sunscreen.
Should I use Tretinoin in the morning or at night?
Tretinoin: best at night. Use only as prescribed: a pea-sized amount on completely dry skin at night, starting 2–3 nights a week. Expect dryness and a possible purge for 4–8 weeks. Daily SPF is essential.
Is Tranexamic Acid with Tretinoin safe during pregnancy?
Tretinoin is generally avoided during pregnancy and breastfeeding. Ask your doctor about safer alternatives such as azelaic acid or bakuchiol.