Glutathione vs Mandelic Acid
Both target pigmentation. Here's how they differ, and whether you should pick one or use both.
| Glutathione | Mandelic Acid | |
|---|---|---|
| Main job | Pigmentation, dullness and antioxidant | Acne, pigmentation and texture |
| Typical strength | 1% – 2% | 5% – 10% |
| Best time | AM/PM | PM |
| Irritation | ||
| Best for | Normal, Oily, Combination, Dry And Sensitive | Sensitive, Oily And Combination |
| Pregnancy | Ask | Safe |
| Price in India | ₹500 – ₹1,800 | ₹500 – ₹1,500 |
The verdict
For pigmentation, Mandelic Acid is the stronger option, while Glutathione is gentler and better suited to sensitive or beginner skin.
Using both? Safe to mix There is no known chemical conflict between Glutathione and Mandelic Acid, and neither makes the other less effective. They share a goal (pigmentation), so together they reinforce each other. How to layer them →
Glutathione in short
A popular "glow" antioxidant in India. Topically it has some evidence for mild brightening, but it is a large, unstable molecule. Expect modest results compared with vitamin C, arbutin or niacinamide.
Mandelic Acid in short
The largest, slowest AHA. Dermatologists often pick it for melanin-rich Indian skin tones because it treats acne and pigmentation with a lower risk of post-inflammatory darkening.
Not sure which fits your skin?
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