Glutathione vs Niacinamide
Both target pigmentation. Here's how they differ, and whether you should pick one or use both.
| Glutathione | Niacinamide | |
|---|---|---|
| Main job | Pigmentation, dullness and antioxidant | Oil control, pigmentation, barrier, acne and redness |
| Typical strength | 1% – 2% | 2% – 10% |
| Best time | AM/PM | AM/PM |
| Irritation | ||
| Best for | Normal, Oily, Combination, Dry And Sensitive | Oily, Combination, Normal, Sensitive And Dry |
| Pregnancy | Ask | Safe |
| Price in India | ₹500 – ₹1,800 | ₹300 – ₹1,200 |
The verdict
For pigmentation, Niacinamide is the stronger option, while Glutathione is gentler and better suited to sensitive or beginner skin.
Using both? Safe to mix There is no known chemical conflict between Glutathione and Niacinamide, and neither makes the other less effective. They share a goal (pigmentation), so together they reinforce each other. How to layer them →
Glutathione in short
A popular "glow" antioxidant in India. Topically it has some evidence for mild brightening, but it is a large, unstable molecule. Expect modest results compared with vitamin C, arbutin or niacinamide.
Niacinamide in short
An all-rounder that controls oil, strengthens the skin barrier, reduces redness and evens out tone. It gets along with almost every other active, which is why it is in so many routines.
Not sure which fits your skin?
The routine builder picks actives for your skin type, concern and climate automatically.