How to use them
Use them in the same routine morning or night. Apply Alpha Arbutin first, then PDRN, moving from thinnest to thickest texture. Finish with sunscreen in the morning.
- 1CleanseGentle cleanser, pat dry
- 2Alpha Arbutin1% – 2%, wait about 1 minute
- 3PDRNvaries (often with PN/polynucleotides blends)
- 4Moisturiserseal everything in
What Alpha Arbutin does
A skin-friendly relative of hydroquinone that slows melanin production. It fades dark spots and tanning gradually with very little irritation.
- Typical strength
- 1% – 2%
- When
- AM/PM
- Irritation
- Best for
- Normal, Oily, Combination, Dry And Sensitive skin
Everything that pairs with Alpha Arbutin →
What PDRN does
Polydeoxyribonucleotide, a salmon-DNA-derived ingredient best known from in-clinic "salmon DNA" injections and now sold in serums. Early clinical studies suggest it may support tissue repair and hydration, but topical (as opposed to injected) evidence is still limited, so treat claims of dramatic results with caution.
- Typical strength
- varies (often with PN/polynucleotides blends)
- When
- AM/PM
- Irritation
- Best for
- Normal, Dry, Sensitive And Combination skin
Everything that pairs with PDRN →
Frequently asked questions
Can I use Alpha Arbutin and PDRN together?
Yes, it is safe. There is no known chemical conflict between Alpha Arbutin and PDRN, and neither makes the other less effective.
Which goes first, Alpha Arbutin or PDRN?
Apply Alpha Arbutin first, then PDRN. The general rule is thinnest to thickest texture, and lowest pH first.
Should I use Alpha Arbutin in the morning or at night?
Alpha Arbutin: works morning or night. Apply twice daily before heavier serums and creams.
Should I use PDRN in the morning or at night?
PDRN: works morning or night. Use as a serum step, morning or night. It has no known irritancy, so it layers easily with most other actives. It is not a substitute for an in-clinic PDRN treatment, which uses injectable-grade material under medical supervision.
Is Alpha Arbutin with PDRN safe during pregnancy?
Neither is a known risk in normal cosmetic amounts, but guidance varies for PDRN. Check with your doctor.