PDRN: Benefits & What to Mix It With

PDRN: what to mix it with

Polydeoxyribonucleotide, a salmon-DNA-derived ingredient best known from in-clinic "salmon DNA" injections and now sold in serums. Early clinical studies suggest it may support tissue repair and hydration, but topical (as opposed to injected) evidence is still limited, so treat claims of dramatic results with caution.

Typical strength: varies (often with PN/polynucleotides blends)
Best time: AM/PM
Irritation
Price in India: ₹1,200 – ₹4,000
Helps with: Aging, barrier and hydration
Pregnancy: Ask your doctor before using in pregnancy

How to use PDRN

Use as a serum step, morning or night. It has no known irritancy, so it layers easily with most other actives. It is not a substitute for an in-clinic PDRN treatment, which uses injectable-grade material under medical supervision.

Pairs beautifully with

Sunscreen

Use at different times from

Glycolic Acid Lactic Acid Mandelic Acid Salicylic Acid PHA Benzoyl Peroxide

Safe to layer with

Retinol Adapalene Vitamin C Niacinamide Azelaic Acid Hyaluronic Acid Peptides Copper Peptides Ceramides Bakuchiol Tranexamic Acid Alpha Arbutin Kojic Acid Centella Asiatica Squalane Vitamin E Ferulic Acid Snail Mucin Panthenol Tretinoin Retinal Hydroquinone Sulfur Tea Tree Oil Aloe Vera Licorice Extract Urea Glutathione Zinc PCA Polyglutamic Acid Exosomes

Guides

Ingredients for fine lines & anti-ageing Ingredients for dehydrated & dry skin Ingredients for damaged skin barrier Is PDRN safe in pregnancy?

PDRN: what to mix it with