Beauty Elixir

Can you use Bakuchiol with Tretinoin?

Safe to mix

Yes, it is safe.

There is no known chemical conflict between Bakuchiol and Tretinoin, and neither makes the other less effective. They share a goal (aging, texture and pigmentation), so together they reinforce each other.

How to use them

Use them in the same routine at night. Apply Bakuchiol first, then Tretinoin, moving from thinnest to thickest texture.

  1. 1
    CleanseGentle cleanser, pat dry
  2. 2
    Bakuchiol0.5% – 2%, wait about 1 minute
  3. 3
    Tretinoin0.025% – 0.1% (prescription)
  4. 4
    Moisturiserseal everything in

What Bakuchiol does

A plant extract (from babchi seeds) that works like retinol in small studies, with far less dryness and no sun sensitivity. It is milder and slower than a true retinoid.

Typical strength
0.5% – 2%
When
AM/PM
Irritation
Best for
Sensitive, Dry And Normal skin

Everything that pairs with Bakuchiol →

What Tretinoin does

The prescription-strength retinoid, and the gold standard for acne and photo-ageing, with decades of evidence. It works directly (no conversion needed), so it is stronger and more irritating than retinol or retinal.

Typical strength
0.025% – 0.1% (prescription)
When
PM
Irritation
Best for
Oily, Normal And Combination skin

Everything that pairs with Tretinoin →

Trying to choose one? Read Bakuchiol vs Tretinoin: which is better for your skin.

Frequently asked questions

Can I use Bakuchiol and Tretinoin together?

Yes, it is safe. There is no known chemical conflict between Bakuchiol and Tretinoin, and neither makes the other less effective. They share a goal (aging, texture and pigmentation), so together they reinforce each other.

Which goes first, Bakuchiol or Tretinoin?

Apply Bakuchiol first, then Tretinoin. The general rule is thinnest to thickest texture, and lowest pH first.

Should I use Bakuchiol in the morning or at night?

Bakuchiol: works morning or night. Use twice daily. It is stable in sunlight, so a morning application is fine.

Should I use Tretinoin in the morning or at night?

Tretinoin: best at night. Use only as prescribed: a pea-sized amount on completely dry skin at night, starting 2–3 nights a week. Expect dryness and a possible purge for 4–8 weeks. Daily SPF is essential.

Is Bakuchiol with Tretinoin safe during pregnancy?

Tretinoin is generally avoided during pregnancy and breastfeeding. Ask your doctor about safer alternatives such as azelaic acid or bakuchiol.

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