How to use them
Use them in the same routine morning or night. Apply Centella Asiatica first, then PDRN, moving from thinnest to thickest texture. Finish with sunscreen in the morning.
- 1CleanseGentle cleanser, pat dry
- 2Centella Asiaticavaries, wait about 1 minute
- 3PDRNvaries (often with PN/polynucleotides blends)
- 4Moisturiserseal everything in
What Centella Asiatica does
The K-beauty hero known as cica (in India, gotu kola or brahmi). It calms irritation and redness and helps a stressed barrier recover. That makes it a perfect sidekick to strong actives.
- Typical strength
- varies
- When
- AM/PM
- Irritation
- Best for
- Sensitive, Oily, Combination, Normal And Dry skin
Everything that pairs with Centella Asiatica →
What PDRN does
Polydeoxyribonucleotide, a salmon-DNA-derived ingredient best known from in-clinic "salmon DNA" injections and now sold in serums. Early clinical studies suggest it may support tissue repair and hydration, but topical (as opposed to injected) evidence is still limited, so treat claims of dramatic results with caution.
- Typical strength
- varies (often with PN/polynucleotides blends)
- When
- AM/PM
- Irritation
- Best for
- Normal, Dry, Sensitive And Combination skin
Everything that pairs with PDRN →
Frequently asked questions
Can I use Centella Asiatica and PDRN together?
Yes, it is safe. There is no known chemical conflict between Centella Asiatica and PDRN, and neither makes the other less effective. They share a goal (barrier), so together they reinforce each other.
Which goes first, Centella Asiatica or PDRN?
Apply Centella Asiatica first, then PDRN. The general rule is thinnest to thickest texture, and lowest pH first.
Should I use Centella Asiatica in the morning or at night?
Centella Asiatica: works morning or night. Use morning and night. It is ideal on the day after an exfoliation or retinoid night.
Should I use PDRN in the morning or at night?
PDRN: works morning or night. Use as a serum step, morning or night. It has no known irritancy, so it layers easily with most other actives. It is not a substitute for an in-clinic PDRN treatment, which uses injectable-grade material under medical supervision.
Is Centella Asiatica with PDRN safe during pregnancy?
Neither is a known risk in normal cosmetic amounts, but guidance varies for PDRN. Check with your doctor.