How to use them
Use them in the same routine at night. Apply Tretinoin first, then Ceramides, moving from thinnest to thickest texture.
- 1CleanseGentle cleanser, pat dry
- 2Tretinoin0.025% – 0.1% (prescription), wait about 1 minute
- 3Ceramidesvaries
- 4Moisturiserseal everything in
What Ceramides does
Lipids that make up about half of your skin barrier. Topping them up reduces water loss, stinging and flakiness, which makes ceramides the best friend of anyone using retinoids or acids.
- Typical strength
- varies
- When
- AM/PM
- Irritation
- Best for
- Dry, Sensitive, Normal, Combination And Oily skin
Everything that pairs with Ceramides →
What Tretinoin does
The prescription-strength retinoid, and the gold standard for acne and photo-ageing, with decades of evidence. It works directly (no conversion needed), so it is stronger and more irritating than retinol or retinal.
- Typical strength
- 0.025% – 0.1% (prescription)
- When
- PM
- Irritation
- Best for
- Oily, Normal And Combination skin
Everything that pairs with Tretinoin →
Frequently asked questions
Can I use Ceramides and Tretinoin together?
Yes, and they work even better together. Ceramides cushions Tretinoin: it hydrates and supports the barrier while the active does its work. That means less irritation and better results.
Which goes first, Ceramides or Tretinoin?
Apply Tretinoin first, then Ceramides. The general rule is thinnest to thickest texture, and lowest pH first.
Should I use Ceramides in the morning or at night?
Ceramides: works morning or night. Use as your moisturiser step, morning and night. On nights with actives, you can buffer by applying a ceramide cream first.
Should I use Tretinoin in the morning or at night?
Tretinoin: best at night. Use only as prescribed: a pea-sized amount on completely dry skin at night, starting 2–3 nights a week. Expect dryness and a possible purge for 4–8 weeks. Daily SPF is essential.
Is Ceramides with Tretinoin safe during pregnancy?
Tretinoin is generally avoided during pregnancy and breastfeeding. Ask your doctor about safer alternatives such as azelaic acid or bakuchiol.