How to use them
Use them in the same routine at night. Apply Glycolic Acid first, then Hydroquinone, moving from thinnest to thickest texture.
- 1CleanseGentle cleanser, pat dry
- 2Glycolic Acid5% – 10%, wait about 1 minute
- 3Hydroquinone2% – 4% (prescription in India)
- 4Moisturiserseal everything in
What Glycolic Acid does
The smallest alpha-hydroxy acid, so it penetrates deepest. It dissolves the bonds between dead skin cells for smoother, brighter skin and fades marks, but it is the AHA most likely to sting.
- Typical strength
- 5% – 10%
- When
- PM
- Irritation
- Best for
- Normal, Oily And Combination skin
Everything that pairs with Glycolic Acid →
What Hydroquinone does
The strongest topical depigmenting agent, used for melasma and stubborn dark spots. It blocks melanin production, but it must be used in short, supervised courses: long-term use can cause irritation and, rarely, ochronosis (blue-black darkening).
- Typical strength
- 2% – 4% (prescription in India)
- When
- PM
- Irritation
- Best for
- Normal, Oily And Combination skin
Everything that pairs with Hydroquinone →
Trying to choose one? Read Glycolic Acid vs Hydroquinone: which is better for your skin.
Frequently asked questions
Can I use Glycolic Acid and Hydroquinone together?
Yes, it is safe. There is no known chemical conflict between Glycolic Acid and Hydroquinone, and neither makes the other less effective. They share a goal (pigmentation), so together they reinforce each other.
Which goes first, Glycolic Acid or Hydroquinone?
Apply Glycolic Acid first, then Hydroquinone. The general rule is thinnest to thickest texture, and lowest pH first.
Should I use Glycolic Acid in the morning or at night?
Glycolic Acid: best at night. Use 2–3 nights a week after cleansing. Skip it on nights you use retinoids. Sunscreen is non-negotiable because AHAs raise sun sensitivity.
Should I use Hydroquinone in the morning or at night?
Hydroquinone: best at night. Use only under a dermatologist's guidance, typically nightly on the dark patches for up to 3 months, then take a break. Strict daily sunscreen is required or results reverse.
Is Glycolic Acid with Hydroquinone safe during pregnancy?
Hydroquinone is generally avoided during pregnancy and breastfeeding. Ask your doctor about safer alternatives such as azelaic acid or bakuchiol.