How to use them
Use them in the same routine at night. Apply Licorice Extract first, then Tretinoin, moving from thinnest to thickest texture.
- 1CleanseGentle cleanser, pat dry
- 2Licorice Extractvaries (glabridin ~0.5%), wait about 1 minute
- 3Tretinoin0.025% – 0.1% (prescription)
- 4Moisturiserseal everything in
What Licorice Extract does
Licorice root (mulethi) contains glabridin, which gently inhibits pigment production, and glycyrrhizinates, which calm redness. It is a mild brightener suited to sensitive skin.
- Typical strength
- varies (glabridin ~0.5%)
- When
- AM/PM
- Irritation
- Best for
- Sensitive, Normal, Combination, Dry And Oily skin
Everything that pairs with Licorice Extract →
What Tretinoin does
The prescription-strength retinoid, and the gold standard for acne and photo-ageing, with decades of evidence. It works directly (no conversion needed), so it is stronger and more irritating than retinol or retinal.
- Typical strength
- 0.025% – 0.1% (prescription)
- When
- PM
- Irritation
- Best for
- Oily, Normal And Combination skin
Everything that pairs with Tretinoin →
Trying to choose one? Read Licorice Extract vs Tretinoin: which is better for your skin.
Frequently asked questions
Can I use Licorice Extract and Tretinoin together?
Yes, it is safe. There is no known chemical conflict between Licorice Extract and Tretinoin, and neither makes the other less effective. They share a goal (pigmentation), so together they reinforce each other.
Which goes first, Licorice Extract or Tretinoin?
Apply Licorice Extract first, then Tretinoin. The general rule is thinnest to thickest texture, and lowest pH first.
Should I use Licorice Extract in the morning or at night?
Licorice Extract: works morning or night. Use once or twice daily. It pairs well with niacinamide, arbutin or vitamin C for dark spots.
Should I use Tretinoin in the morning or at night?
Tretinoin: best at night. Use only as prescribed: a pea-sized amount on completely dry skin at night, starting 2–3 nights a week. Expect dryness and a possible purge for 4–8 weeks. Daily SPF is essential.
Is Licorice Extract with Tretinoin safe during pregnancy?
Tretinoin is generally avoided during pregnancy and breastfeeding. Ask your doctor about safer alternatives such as azelaic acid or bakuchiol.