Beauty Elixir

Can you use Adapalene with Licorice Extract?

Safe to mix

Yes, it is safe.

There is no known chemical conflict between Adapalene and Licorice Extract, and neither makes the other less effective. They share a goal (pigmentation), so together they reinforce each other.

How to use them

Use them in the same routine at night. Apply Licorice Extract first, then Adapalene, moving from thinnest to thickest texture.

  1. 1
    CleanseGentle cleanser, pat dry
  2. 2
    Licorice Extractvaries (glabridin ~0.5%), wait about 1 minute
  3. 3
    Adapalene0.1%
  4. 4
    Moisturiserseal everything in

What Adapalene does

A synthetic retinoid built for acne. It unclogs pores and calms the inflammation behind breakouts. It is more stable than retinol, and in India it is sold as a gel (often by prescription).

Typical strength
0.1%
When
PM
Irritation
Best for
Oily And Combination skin

Everything that pairs with Adapalene →

What Licorice Extract does

Licorice root (mulethi) contains glabridin, which gently inhibits pigment production, and glycyrrhizinates, which calm redness. It is a mild brightener suited to sensitive skin.

Typical strength
varies (glabridin ~0.5%)
When
AM/PM
Irritation
Best for
Sensitive, Normal, Combination, Dry And Oily skin

Everything that pairs with Licorice Extract →

Trying to choose one? Read Adapalene vs Licorice Extract: which is better for your skin.

Frequently asked questions

Can I use Adapalene and Licorice Extract together?

Yes, it is safe. There is no known chemical conflict between Adapalene and Licorice Extract, and neither makes the other less effective. They share a goal (pigmentation), so together they reinforce each other.

Which goes first, Adapalene or Licorice Extract?

Apply Licorice Extract first, then Adapalene. The general rule is thinnest to thickest texture, and lowest pH first.

Should I use Adapalene in the morning or at night?

Adapalene: best at night. Apply a thin layer to the whole acne-prone area at night, not just on spots. Expect a purge for 4–6 weeks. Use a moisturiser and daily SPF.

Should I use Licorice Extract in the morning or at night?

Licorice Extract: works morning or night. Use once or twice daily. It pairs well with niacinamide, arbutin or vitamin C for dark spots.

Is Adapalene with Licorice Extract safe during pregnancy?

Adapalene is generally avoided during pregnancy and breastfeeding. Ask your doctor about safer alternatives such as azelaic acid or bakuchiol.

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