How to use them
Use them in the same routine at night. Apply Glutathione first, then Retinol, moving from thinnest to thickest texture.
- 1CleanseGentle cleanser, pat dry
- 2Glutathione1% – 2%, wait about 1 minute
- 3Retinol0.1% – 1%
- 4Moisturiserseal everything in
What Glutathione does
A popular "glow" antioxidant in India. Topically it has some evidence for mild brightening, but it is a large, unstable molecule. Expect modest results compared with vitamin C, arbutin or niacinamide.
- Typical strength
- 1% – 2%
- When
- AM/PM
- Irritation
- Best for
- Normal, Oily, Combination, Dry And Sensitive skin
Everything that pairs with Glutathione →
What Retinol does
The most studied over-the-counter anti-ageing active. Retinol speeds up cell turnover, softens fine lines, fades marks and keeps pores clear, but it can cause dryness, peeling and sun sensitivity while your skin adjusts.
- Typical strength
- 0.1% – 1%
- When
- PM
- Irritation
- Best for
- Normal, Oily And Combination skin
Everything that pairs with Retinol →
Trying to choose one? Read Glutathione vs Retinol: which is better for your skin.
Frequently asked questions
Can I use Glutathione and Retinol together?
Yes, it is safe. There is no known chemical conflict between Glutathione and Retinol, and neither makes the other less effective. They share a goal (pigmentation), so together they reinforce each other.
Which goes first, Glutathione or Retinol?
Apply Glutathione first, then Retinol. The general rule is thinnest to thickest texture, and lowest pH first.
Should I use Glutathione in the morning or at night?
Glutathione: works morning or night. Use daily as part of a brightening routine, always with sunscreen. Glutathione injections and drips for skin whitening are not approved for that use and carry real risks.
Should I use Retinol in the morning or at night?
Retinol: best at night. Start 2–3 nights a week on dry skin, a pea-sized amount for the whole face, then build up. Always wear sunscreen the next morning.
Is Glutathione with Retinol safe during pregnancy?
Retinol is generally avoided during pregnancy and breastfeeding. Ask your doctor about safer alternatives such as azelaic acid or bakuchiol.