How to use them
Use them in the same routine morning or night. Apply Licorice Extract first, then PDRN, moving from thinnest to thickest texture. Finish with sunscreen in the morning.
- 1CleanseGentle cleanser, pat dry
- 2Licorice Extractvaries (glabridin ~0.5%), wait about 1 minute
- 3PDRNvaries (often with PN/polynucleotides blends)
- 4Moisturiserseal everything in
What Licorice Extract does
Licorice root (mulethi) contains glabridin, which gently inhibits pigment production, and glycyrrhizinates, which calm redness. It is a mild brightener suited to sensitive skin.
- Typical strength
- varies (glabridin ~0.5%)
- When
- AM/PM
- Irritation
- Best for
- Sensitive, Normal, Combination, Dry And Oily skin
Everything that pairs with Licorice Extract →
What PDRN does
Polydeoxyribonucleotide, a salmon-DNA-derived ingredient best known from in-clinic "salmon DNA" injections and now sold in serums. Early clinical studies suggest it may support tissue repair and hydration, but topical (as opposed to injected) evidence is still limited, so treat claims of dramatic results with caution.
- Typical strength
- varies (often with PN/polynucleotides blends)
- When
- AM/PM
- Irritation
- Best for
- Normal, Dry, Sensitive And Combination skin
Everything that pairs with PDRN →
Frequently asked questions
Can I use Licorice Extract and PDRN together?
Yes, it is safe. There is no known chemical conflict between Licorice Extract and PDRN, and neither makes the other less effective.
Which goes first, Licorice Extract or PDRN?
Apply Licorice Extract first, then PDRN. The general rule is thinnest to thickest texture, and lowest pH first.
Should I use Licorice Extract in the morning or at night?
Licorice Extract: works morning or night. Use once or twice daily. It pairs well with niacinamide, arbutin or vitamin C for dark spots.
Should I use PDRN in the morning or at night?
PDRN: works morning or night. Use as a serum step, morning or night. It has no known irritancy, so it layers easily with most other actives. It is not a substitute for an in-clinic PDRN treatment, which uses injectable-grade material under medical supervision.
Is Licorice Extract with PDRN safe during pregnancy?
Neither is a known risk in normal cosmetic amounts, but guidance varies for PDRN. Check with your doctor.