Beauty Elixir

Can you use Niacinamide with Retinal?

Safe to mix

Yes, it is safe.

There is no known chemical conflict between Niacinamide and Retinal, and neither makes the other less effective. They share a goal (pigmentation and acne), so together they reinforce each other.

How to use them

Use them in the same routine at night. Apply Niacinamide first, then Retinal, moving from thinnest to thickest texture.

  1. 1
    CleanseGentle cleanser, pat dry
  2. 2
    Niacinamide2% – 10%, wait about 1 minute
  3. 3
    Retinal0.05% – 0.2%
  4. 4
    Moisturiserseal everything in

What Niacinamide does

An all-rounder that controls oil, strengthens the skin barrier, reduces redness and evens out tone. It gets along with almost every other active, which is why it is in so many routines.

Typical strength
2% – 10%
When
AM/PM
Irritation
Best for
Oily, Combination, Normal, Sensitive And Dry skin

Everything that pairs with Niacinamide →

What Retinal does

Retinaldehyde is one conversion step closer to retinoic acid than retinol, so it works faster than retinol while usually being gentler than tretinoin. It also has a mild antibacterial effect useful for acne.

Typical strength
0.05% – 0.2%
When
PM
Irritation
Best for
Normal, Oily, Combination And Dry skin

Everything that pairs with Retinal →

Trying to choose one? Read Niacinamide vs Retinal: which is better for your skin.

Frequently asked questions

Can I use Niacinamide and Retinal together?

Yes, it is safe. There is no known chemical conflict between Niacinamide and Retinal, and neither makes the other less effective. They share a goal (pigmentation and acne), so together they reinforce each other.

Which goes first, Niacinamide or Retinal?

Apply Niacinamide first, then Retinal. The general rule is thinnest to thickest texture, and lowest pH first.

Should I use Niacinamide in the morning or at night?

Niacinamide: works morning or night. Use morning, night or both, after water-based serums. 4–5% is enough for most people. Very high percentages can cause flushing on sensitive skin.

Should I use Retinal in the morning or at night?

Retinal: best at night. Start at 0.05% two or three nights a week and build up slowly. Buffer with moisturiser if you are sensitive, and wear SPF daily.

Is Niacinamide with Retinal safe during pregnancy?

Retinal is generally avoided during pregnancy and breastfeeding. Ask your doctor about safer alternatives such as azelaic acid or bakuchiol.

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