How to use them
Use them in the same routine at night. Apply Niacinamide first, then Adapalene, moving from thinnest to thickest texture.
- 1CleanseGentle cleanser, pat dry
- 2Niacinamide2% – 10%, wait about 1 minute
- 3Adapalene0.1%
- 4Moisturiserseal everything in
What Adapalene does
A synthetic retinoid built for acne. It unclogs pores and calms the inflammation behind breakouts. It is more stable than retinol, and in India it is sold as a gel (often by prescription).
- Typical strength
- 0.1%
- When
- PM
- Irritation
- Best for
- Oily And Combination skin
Everything that pairs with Adapalene →
What Niacinamide does
An all-rounder that controls oil, strengthens the skin barrier, reduces redness and evens out tone. It gets along with almost every other active, which is why it is in so many routines.
- Typical strength
- 2% – 10%
- When
- AM/PM
- Irritation
- Best for
- Oily, Combination, Normal, Sensitive And Dry skin
Everything that pairs with Niacinamide →
Trying to choose one? Read Adapalene vs Niacinamide: which is better for your skin.
Frequently asked questions
Can I use Adapalene and Niacinamide together?
Yes, and they work even better together. Niacinamide calms the redness and dryness adapalene causes and adds its own anti-acne, oil-controlling effect.
Which goes first, Adapalene or Niacinamide?
Apply Niacinamide first, then Adapalene. The general rule is thinnest to thickest texture, and lowest pH first.
Should I use Adapalene in the morning or at night?
Adapalene: best at night. Apply a thin layer to the whole acne-prone area at night, not just on spots. Expect a purge for 4–6 weeks. Use a moisturiser and daily SPF.
Should I use Niacinamide in the morning or at night?
Niacinamide: works morning or night. Use morning, night or both, after water-based serums. 4–5% is enough for most people. Very high percentages can cause flushing on sensitive skin.
Is Adapalene with Niacinamide safe during pregnancy?
Adapalene is generally avoided during pregnancy and breastfeeding. Ask your doctor about safer alternatives such as azelaic acid or bakuchiol.