How to use them
Use them in the same routine at night. Apply Peptides first, then Retinol, moving from thinnest to thickest texture.
- 1CleanseGentle cleanser, pat dry
- 2Peptidesvaries, wait about 1 minute
- 3Retinol0.1% – 1%
- 4Moisturiserseal everything in
What Peptides does
Short chains of amino acids that signal skin to support collagen and repair. They are gentle, a good anti-ageing option for people who cannot tolerate retinoids, and they layer easily.
- Typical strength
- varies
- When
- AM/PM
- Irritation
- Best for
- Dry, Normal, Sensitive And Combination skin
Everything that pairs with Peptides →
What Retinol does
The most studied over-the-counter anti-ageing active. Retinol speeds up cell turnover, softens fine lines, fades marks and keeps pores clear, but it can cause dryness, peeling and sun sensitivity while your skin adjusts.
- Typical strength
- 0.1% – 1%
- When
- PM
- Irritation
- Best for
- Normal, Oily And Combination skin
Everything that pairs with Retinol →
Trying to choose one? Read Peptides vs Retinol: which is better for your skin.
Frequently asked questions
Can I use Peptides and Retinol together?
Yes, it is safe. Peptides do not interfere with retinol and may help your skin tolerate it. The pair works well in anti-ageing night routines.
Which goes first, Peptides or Retinol?
Apply Peptides first, then Retinol. The general rule is thinnest to thickest texture, and lowest pH first.
Should I use Peptides in the morning or at night?
Peptides: works morning or night. Use morning and night after water-based serums. Low-pH acids applied at the same time can break some peptides down.
Should I use Retinol in the morning or at night?
Retinol: best at night. Start 2–3 nights a week on dry skin, a pea-sized amount for the whole face, then build up. Always wear sunscreen the next morning.
Is Peptides with Retinol safe during pregnancy?
Retinol is generally avoided during pregnancy and breastfeeding. Ask your doctor about safer alternatives such as azelaic acid or bakuchiol.