How to use them
Use them in the same routine at night. Apply Peptides first, then Adapalene, moving from thinnest to thickest texture.
- 1CleanseGentle cleanser, pat dry
- 2Peptidesvaries, wait about 1 minute
- 3Adapalene0.1%
- 4Moisturiserseal everything in
What Adapalene does
A synthetic retinoid built for acne. It unclogs pores and calms the inflammation behind breakouts. It is more stable than retinol, and in India it is sold as a gel (often by prescription).
- Typical strength
- 0.1%
- When
- PM
- Irritation
- Best for
- Oily And Combination skin
Everything that pairs with Adapalene →
What Peptides does
Short chains of amino acids that signal skin to support collagen and repair. They are gentle, a good anti-ageing option for people who cannot tolerate retinoids, and they layer easily.
- Typical strength
- varies
- When
- AM/PM
- Irritation
- Best for
- Dry, Normal, Sensitive And Combination skin
Everything that pairs with Peptides →
Frequently asked questions
Can I use Adapalene and Peptides together?
Yes, it is safe. There is no known chemical conflict between Adapalene and Peptides, and neither makes the other less effective.
Which goes first, Adapalene or Peptides?
Apply Peptides first, then Adapalene. The general rule is thinnest to thickest texture, and lowest pH first.
Should I use Adapalene in the morning or at night?
Adapalene: best at night. Apply a thin layer to the whole acne-prone area at night, not just on spots. Expect a purge for 4–6 weeks. Use a moisturiser and daily SPF.
Should I use Peptides in the morning or at night?
Peptides: works morning or night. Use morning and night after water-based serums. Low-pH acids applied at the same time can break some peptides down.
Is Adapalene with Peptides safe during pregnancy?
Adapalene is generally avoided during pregnancy and breastfeeding. Ask your doctor about safer alternatives such as azelaic acid or bakuchiol.