Beauty Elixir

Can you use Glutathione with Licorice Extract?

Safe to mix

Yes, it is safe.

There is no known chemical conflict between Glutathione and Licorice Extract, and neither makes the other less effective. They share a goal (pigmentation), so together they reinforce each other.

How to use them

Use them in the same routine morning or night. Apply Glutathione first, then Licorice Extract, moving from thinnest to thickest texture. Finish with sunscreen in the morning.

  1. 1
    CleanseGentle cleanser, pat dry
  2. 2
    Glutathione1% – 2%, wait about 1 minute
  3. 3
    Licorice Extractvaries (glabridin ~0.5%)
  4. 4
    Moisturiserseal everything in

What Glutathione does

A popular "glow" antioxidant in India. Topically it has some evidence for mild brightening, but it is a large, unstable molecule. Expect modest results compared with vitamin C, arbutin or niacinamide.

Typical strength
1% – 2%
When
AM/PM
Irritation
Best for
Normal, Oily, Combination, Dry And Sensitive skin

Everything that pairs with Glutathione →

What Licorice Extract does

Licorice root (mulethi) contains glabridin, which gently inhibits pigment production, and glycyrrhizinates, which calm redness. It is a mild brightener suited to sensitive skin.

Typical strength
varies (glabridin ~0.5%)
When
AM/PM
Irritation
Best for
Sensitive, Normal, Combination, Dry And Oily skin

Everything that pairs with Licorice Extract →

Trying to choose one? Read Glutathione vs Licorice Extract: which is better for your skin.

Frequently asked questions

Can I use Glutathione and Licorice Extract together?

Yes, it is safe. There is no known chemical conflict between Glutathione and Licorice Extract, and neither makes the other less effective. They share a goal (pigmentation), so together they reinforce each other.

Which goes first, Glutathione or Licorice Extract?

Apply Glutathione first, then Licorice Extract. The general rule is thinnest to thickest texture, and lowest pH first.

Should I use Glutathione in the morning or at night?

Glutathione: works morning or night. Use daily as part of a brightening routine, always with sunscreen. Glutathione injections and drips for skin whitening are not approved for that use and carry real risks.

Should I use Licorice Extract in the morning or at night?

Licorice Extract: works morning or night. Use once or twice daily. It pairs well with niacinamide, arbutin or vitamin C for dark spots.

Is Glutathione with Licorice Extract safe during pregnancy?

Neither is a known risk in normal cosmetic amounts, but guidance varies for Glutathione. Check with your doctor.

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