Beauty Elixir

Can you use Glutathione with Polyglutamic Acid?

Safe to mix

Yes, it is safe.

There is no known chemical conflict between Glutathione and Polyglutamic Acid, and neither makes the other less effective.

How to use them

Use them in the same routine morning or night. Apply Polyglutamic Acid first, then Glutathione, moving from thinnest to thickest texture. Finish with sunscreen in the morning.

  1. 1
    CleanseGentle cleanser, pat dry
  2. 2
    Polyglutamic Acid1% – 3%, wait about 1 minute
  3. 3
    Glutathione1% – 2%
  4. 4
    Moisturiserseal everything in

What Glutathione does

A popular "glow" antioxidant in India. Topically it has some evidence for mild brightening, but it is a large, unstable molecule. Expect modest results compared with vitamin C, arbutin or niacinamide.

Typical strength
1% – 2%
When
AM/PM
Irritation
Best for
Normal, Oily, Combination, Dry And Sensitive skin

Everything that pairs with Glutathione →

What Polyglutamic Acid does

A bigger-molecule humectant that forms a moisture-holding film on the skin. It is often paired with hyaluronic acid for plump, long-lasting hydration.

Typical strength
1% – 3%
When
AM/PM
Irritation
Best for
Dry, Normal, Combination, Sensitive And Oily skin

Everything that pairs with Polyglutamic Acid →

Frequently asked questions

Can I use Glutathione and Polyglutamic Acid together?

Yes, it is safe. There is no known chemical conflict between Glutathione and Polyglutamic Acid, and neither makes the other less effective.

Which goes first, Glutathione or Polyglutamic Acid?

Apply Polyglutamic Acid first, then Glutathione. The general rule is thinnest to thickest texture, and lowest pH first.

Should I use Glutathione in the morning or at night?

Glutathione: works morning or night. Use daily as part of a brightening routine, always with sunscreen. Glutathione injections and drips for skin whitening are not approved for that use and carry real risks.

Should I use Polyglutamic Acid in the morning or at night?

Polyglutamic Acid: works morning or night. Apply after toner and before moisturiser, morning or night.

Is Glutathione with Polyglutamic Acid safe during pregnancy?

Neither is a known risk in normal cosmetic amounts, but guidance varies for Glutathione. Check with your doctor.

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