How to use them
Use them in the same routine at night. Apply Polyglutamic Acid first, then Hydroquinone, moving from thinnest to thickest texture.
- 1CleanseGentle cleanser, pat dry
- 2Polyglutamic Acid1% – 3%, wait about 1 minute
- 3Hydroquinone2% – 4% (prescription in India)
- 4Moisturiserseal everything in
What Hydroquinone does
The strongest topical depigmenting agent, used for melasma and stubborn dark spots. It blocks melanin production, but it must be used in short, supervised courses: long-term use can cause irritation and, rarely, ochronosis (blue-black darkening).
- Typical strength
- 2% – 4% (prescription in India)
- When
- PM
- Irritation
- Best for
- Normal, Oily And Combination skin
Everything that pairs with Hydroquinone →
What Polyglutamic Acid does
A bigger-molecule humectant that forms a moisture-holding film on the skin. It is often paired with hyaluronic acid for plump, long-lasting hydration.
- Typical strength
- 1% – 3%
- When
- AM/PM
- Irritation
- Best for
- Dry, Normal, Combination, Sensitive And Oily skin
Everything that pairs with Polyglutamic Acid →
Frequently asked questions
Can I use Hydroquinone and Polyglutamic Acid together?
Yes, it is safe. There is no known chemical conflict between Hydroquinone and Polyglutamic Acid, and neither makes the other less effective.
Which goes first, Hydroquinone or Polyglutamic Acid?
Apply Polyglutamic Acid first, then Hydroquinone. The general rule is thinnest to thickest texture, and lowest pH first.
Should I use Hydroquinone in the morning or at night?
Hydroquinone: best at night. Use only under a dermatologist's guidance, typically nightly on the dark patches for up to 3 months, then take a break. Strict daily sunscreen is required or results reverse.
Should I use Polyglutamic Acid in the morning or at night?
Polyglutamic Acid: works morning or night. Apply after toner and before moisturiser, morning or night.
Is Hydroquinone with Polyglutamic Acid safe during pregnancy?
Hydroquinone is generally avoided during pregnancy and breastfeeding. Ask your doctor about safer alternatives such as azelaic acid or bakuchiol.