Beauty Elixir

Differin

Adapalene: what to mix it with

A synthetic retinoid built for acne. It unclogs pores and calms the inflammation behind breakouts. It is more stable than retinol, and in India it is sold as a gel (often by prescription).

Typical strength
0.1%
Best time
PM
Irritation
Price in India
₹200 – ₹700
Helps with
Acne, texture and pigmentation
Pregnancy
Usually avoided in pregnancy and breastfeeding

How to use Adapalene

Apply a thin layer to the whole acne-prone area at night, not just on spots. Expect a purge for 4–6 weeks. Use a moisturiser and daily SPF.

Pairs beautifully with

Niacinamide Hyaluronic Acid Ceramides Centella Asiatica Squalane Sunscreen Snail Mucin Panthenol Aloe Vera Urea Polyglutamic Acid

Don't mix with

Retinol Tretinoin Retinal

Use at different times from

Vitamin C Glycolic Acid Lactic Acid Mandelic Acid Salicylic Acid PHA Benzoyl Peroxide Copper Peptides Sulfur

Safe to layer with

Azelaic Acid Peptides Bakuchiol Tranexamic Acid Alpha Arbutin Kojic Acid Vitamin E Ferulic Acid Hydroquinone Tea Tree Oil Licorice Extract Glutathione Zinc PCA

Guides

Ingredients for acne & breakoutsIngredients for dark spots, tanning & pigmentationIngredients for uneven texture & bumps Is Adapalene safe in pregnancy?

Adapalene vs alternatives

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