Beauty Elixir

Can you use Adapalene with Squalane?

Great combo

Yes, and they work even better together.

Squalane cushions Adapalene: it hydrates and supports the barrier while the active does its work. That means less irritation and better results.

How to use them

Use them in the same routine at night. Apply Adapalene first, then Squalane, moving from thinnest to thickest texture.

  1. 1
    CleanseGentle cleanser, pat dry
  2. 2
    Adapalene0.1%, wait about 1 minute
  3. 3
    Squalaneup to 100%
  4. 4
    Moisturiserseal everything in

What Adapalene does

A synthetic retinoid built for acne. It unclogs pores and calms the inflammation behind breakouts. It is more stable than retinol, and in India it is sold as a gel (often by prescription).

Typical strength
0.1%
When
PM
Irritation
Best for
Oily And Combination skin

Everything that pairs with Adapalene →

What Squalane does

A lightweight, stable oil that mimics your skin's own sebum. It softens and seals in moisture without clogging pores, so even oily skin usually tolerates it.

Typical strength
up to 100%
When
AM/PM
Irritation
Best for
Dry, Normal, Combination, Sensitive And Oily skin

Everything that pairs with Squalane →

Frequently asked questions

Can I use Adapalene and Squalane together?

Yes, and they work even better together. Squalane cushions Adapalene: it hydrates and supports the barrier while the active does its work. That means less irritation and better results.

Which goes first, Adapalene or Squalane?

Apply Adapalene first, then Squalane. The general rule is thinnest to thickest texture, and lowest pH first.

Should I use Adapalene in the morning or at night?

Adapalene: best at night. Apply a thin layer to the whole acne-prone area at night, not just on spots. Expect a purge for 4–6 weeks. Use a moisturiser and daily SPF.

Should I use Squalane in the morning or at night?

Squalane: works morning or night. Press 2–3 drops in as the last step at night, or mix a drop into your moisturiser.

Is Adapalene with Squalane safe during pregnancy?

Adapalene is generally avoided during pregnancy and breastfeeding. Ask your doctor about safer alternatives such as azelaic acid or bakuchiol.

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