How to use them
Alternate nights, for example Adapalene on Monday, Wednesday and Friday and Copper Peptides on Tuesday and Thursday, with a plain moisturiser night in between if your skin feels sensitive. If your skin is resilient and already used to both, you can try layering them: apply Copper Peptides first, wait a few minutes, then apply Adapalene.
- 1CleanseGentle cleanser, pat dry
- AMCopper Peptides (day 1)then moisturiser and SPF 50
- PMAdapalene (day 2)then moisturiser
What Adapalene does
A synthetic retinoid built for acne. It unclogs pores and calms the inflammation behind breakouts. It is more stable than retinol, and in India it is sold as a gel (often by prescription).
- Typical strength
- 0.1%
- When
- PM
- Irritation
- Best for
- Oily And Combination skin
Everything that pairs with Adapalene →
What Copper Peptides does
A peptide bound to copper that supports wound-healing, firmness and barrier repair. Copper is reactive, so it does not play well with strong acids or pure vitamin C.
- Typical strength
- 0.1% – 1%
- When
- PM
- Irritation
- Best for
- Normal, Dry And Combination skin
Everything that pairs with Copper Peptides →
Frequently asked questions
Can I use Adapalene and Copper Peptides together?
Yes, but not at the same time. There is no dangerous reaction, but both are potent and copper peptides are thought to work best on their own. Most people use them on alternate nights.
Which goes first, Adapalene or Copper Peptides?
Apply Copper Peptides first, then Adapalene. The general rule is thinnest to thickest texture, and lowest pH first. For this pair, though, it is better not to layer them in the same routine at all.
Should I use Adapalene in the morning or at night?
Adapalene: best at night. Apply a thin layer to the whole acne-prone area at night, not just on spots. Expect a purge for 4–6 weeks. Use a moisturiser and daily SPF.
Should I use Copper Peptides in the morning or at night?
Copper Peptides: best at night. Use at night on nights without acids or vitamin C. A thin layer is enough.
Is Adapalene with Copper Peptides safe during pregnancy?
Adapalene is generally avoided during pregnancy and breastfeeding. Ask your doctor about safer alternatives such as azelaic acid or bakuchiol.