How to use them
Use them in the same routine at night. Apply Exosomes first, then Adapalene, moving from thinnest to thickest texture.
- 1CleanseGentle cleanser, pat dry
- 2Exosomesvaries (plant- or stem-cell-derived), wait about 1 minute
- 3Adapalene0.1%
- 4Moisturiserseal everything in
What Adapalene does
A synthetic retinoid built for acne. It unclogs pores and calms the inflammation behind breakouts. It is more stable than retinol, and in India it is sold as a gel (often by prescription).
- Typical strength
- 0.1%
- When
- PM
- Irritation
- Best for
- Oily And Combination skin
Everything that pairs with Adapalene →
What Exosomes does
Tiny cell-signalling particles, most often derived from plant or stem-cell cultures for cosmetic use. In-clinic exosome treatments (injected or applied after microneedling) have more published evidence than the topical serums sold direct to consumers. Regulatory status varies by country, and topical evidence is still described as early and limited, so treat "regeneration" or anti-ageing claims with caution.
- Typical strength
- varies (plant- or stem-cell-derived)
- When
- AM/PM
- Irritation
- Best for
- Normal, Dry, Combination And Sensitive skin
Everything that pairs with Exosomes →
Trying to choose one? Read Adapalene vs Exosomes: which is better for your skin.
Frequently asked questions
Can I use Adapalene and Exosomes together?
Yes, it is safe. There is no known chemical conflict between Adapalene and Exosomes, and neither makes the other less effective. They share a goal (texture), so together they reinforce each other.
Which goes first, Adapalene or Exosomes?
Apply Exosomes first, then Adapalene. The general rule is thinnest to thickest texture, and lowest pH first.
Should I use Adapalene in the morning or at night?
Adapalene: best at night. Apply a thin layer to the whole acne-prone area at night, not just on spots. Expect a purge for 4–6 weeks. Use a moisturiser and daily SPF.
Should I use Exosomes in the morning or at night?
Exosomes: works morning or night. If using a topical exosome serum, apply after cleansing and before heavier creams. For in-clinic exosome treatments, use only a qualified, licensed practitioner and ask what the exosomes are derived from.
Is Adapalene with Exosomes safe during pregnancy?
Adapalene is generally avoided during pregnancy and breastfeeding. Ask your doctor about safer alternatives such as azelaic acid or bakuchiol.