How to use them
Choose one retinoid and use it 2–4 nights a week. Fill the other nights with hydrating and barrier-repair products.
- 1CleanseGentle cleanser, pat dry
- AMAdapalene (day 1)then moisturiser and SPF 50
- PMRetinol (day 2)then moisturiser
What Adapalene does
A synthetic retinoid built for acne. It unclogs pores and calms the inflammation behind breakouts. It is more stable than retinol, and in India it is sold as a gel (often by prescription).
- Typical strength
- 0.1%
- When
- PM
- Irritation
- Best for
- Oily And Combination skin
Everything that pairs with Adapalene →
What Retinol does
The most studied over-the-counter anti-ageing active. Retinol speeds up cell turnover, softens fine lines, fades marks and keeps pores clear, but it can cause dryness, peeling and sun sensitivity while your skin adjusts.
- Typical strength
- 0.1% – 1%
- When
- PM
- Irritation
- Best for
- Normal, Oily And Combination skin
Everything that pairs with Retinol →
Trying to choose one? Read Adapalene vs Retinol: which is better for your skin.
Frequently asked questions
Can I use Adapalene and Retinol together?
No, keep them apart. Adapalene and Retinol are both retinoids. Doubling up does not double results. It just doubles the dryness, peeling and irritation. Pick one.
Which goes first, Adapalene or Retinol?
Apply Adapalene first, then Retinol. The general rule is thinnest to thickest texture, and lowest pH first. For this pair, though, it is better not to layer them in the same routine at all.
Should I use Adapalene in the morning or at night?
Adapalene: best at night. Apply a thin layer to the whole acne-prone area at night, not just on spots. Expect a purge for 4–6 weeks. Use a moisturiser and daily SPF.
Should I use Retinol in the morning or at night?
Retinol: best at night. Start 2–3 nights a week on dry skin, a pea-sized amount for the whole face, then build up. Always wear sunscreen the next morning.
Is Adapalene with Retinol safe during pregnancy?
Adapalene and Retinol is generally avoided during pregnancy and breastfeeding. Ask your doctor about safer alternatives such as azelaic acid or bakuchiol.