How to use them
Split them up: use Vitamin C in your morning routine (under sunscreen) and Adapalene at night.
- 1CleanseGentle cleanser, pat dry
- AMVitamin Cthen moisturiser and SPF 50
- PMAdapalenethen moisturiser
What Adapalene does
A synthetic retinoid built for acne. It unclogs pores and calms the inflammation behind breakouts. It is more stable than retinol, and in India it is sold as a gel (often by prescription).
- Typical strength
- 0.1%
- When
- PM
- Irritation
- Best for
- Oily And Combination skin
Everything that pairs with Adapalene →
What Vitamin C does
A powerful antioxidant that brightens dull skin, fades dark spots and boosts your sunscreen's protection against free radicals. Pure L-ascorbic acid works best at a low pH and oxidises (turns orange) quickly.
- Typical strength
- 10% – 20%
- When
- AM
- Irritation
- Best for
- Normal, Oily, Combination And Dry skin
Everything that pairs with Vitamin C →
Trying to choose one? Read Adapalene vs Vitamin C: which is better for your skin.
Frequently asked questions
Can I use Adapalene and Vitamin C together?
Yes, but not at the same time. These do not cancel each other out, but both can irritate, and they work best at different pH levels. The easy fix is vitamin C in the morning (where its antioxidant protection matters most) and the retinoid at night.
Which goes first, Adapalene or Vitamin C?
Apply Vitamin C first, then Adapalene. The general rule is thinnest to thickest texture, and lowest pH first. For this pair, though, it is better not to layer them in the same routine at all.
Should I use Adapalene in the morning or at night?
Adapalene: best at night. Apply a thin layer to the whole acne-prone area at night, not just on spots. Expect a purge for 4–6 weeks. Use a moisturiser and daily SPF.
Should I use Vitamin C in the morning or at night?
Vitamin C: best in the morning. Apply in the morning on clean skin before moisturiser and sunscreen. Store it away from light and heat, and throw it out once it turns dark orange.
Is Adapalene with Vitamin C safe during pregnancy?
Adapalene is generally avoided during pregnancy and breastfeeding. Ask your doctor about safer alternatives such as azelaic acid or bakuchiol.