How to use them
Use them in the same routine at night. Apply Adapalene first, then Vitamin E, moving from thinnest to thickest texture.
- 1CleanseGentle cleanser, pat dry
- 2Adapalene0.1%, wait about 1 minute
- 3Vitamin E0.5% – 1%
- 4Moisturiserseal everything in
What Adapalene does
A synthetic retinoid built for acne. It unclogs pores and calms the inflammation behind breakouts. It is more stable than retinol, and in India it is sold as a gel (often by prescription).
- Typical strength
- 0.1%
- When
- PM
- Irritation
- Best for
- Oily And Combination skin
Everything that pairs with Adapalene →
What Vitamin E does
An oil-soluble antioxidant that protects skin lipids from damage and noticeably stabilises vitamin C. It is heavy in pure form, so it is better inside formulas than straight from a capsule.
- Typical strength
- 0.5% – 1%
- When
- AM/PM
- Irritation
- Best for
- Dry, Normal And Sensitive skin
Everything that pairs with Vitamin E →
Frequently asked questions
Can I use Adapalene and Vitamin E together?
Yes, it is safe. There is no known chemical conflict between Adapalene and Vitamin E, and neither makes the other less effective.
Which goes first, Adapalene or Vitamin E?
Apply Adapalene first, then Vitamin E. The general rule is thinnest to thickest texture, and lowest pH first.
Should I use Adapalene in the morning or at night?
Adapalene: best at night. Apply a thin layer to the whole acne-prone area at night, not just on spots. Expect a purge for 4–6 weeks. Use a moisturiser and daily SPF.
Should I use Vitamin E in the morning or at night?
Vitamin E: works morning or night. Look for it combined with vitamin C and ferulic acid. Very oily or acne-prone skin should avoid pure vitamin E oil.
Is Adapalene with Vitamin E safe during pregnancy?
Adapalene is generally avoided during pregnancy and breastfeeding. Ask your doctor about safer alternatives such as azelaic acid or bakuchiol.