Beauty Elixir

Can you use Retinal with Zinc PCA?

Safe to mix

Yes, it is safe.

There is no known chemical conflict between Retinal and Zinc PCA, and neither makes the other less effective. They share a goal (acne), so together they reinforce each other.

How to use them

Use them in the same routine at night. Apply Zinc PCA first, then Retinal, moving from thinnest to thickest texture.

  1. 1
    CleanseGentle cleanser, pat dry
  2. 2
    Zinc PCA1%, wait about 1 minute
  3. 3
    Retinal0.05% – 0.2%
  4. 4
    Moisturiserseal everything in

What Retinal does

Retinaldehyde is one conversion step closer to retinoic acid than retinol, so it works faster than retinol while usually being gentler than tretinoin. It also has a mild antibacterial effect useful for acne.

Typical strength
0.05% – 0.2%
When
PM
Irritation
Best for
Normal, Oily, Combination And Dry skin

Everything that pairs with Retinal →

What Zinc PCA does

Zinc salts help regulate sebum and have mild anti-inflammatory and antibacterial effects. That is why zinc so often appears next to niacinamide in oil-control serums.

Typical strength
1%
When
AM/PM
Irritation
Best for
Oily And Combination skin

Everything that pairs with Zinc PCA →

Trying to choose one? Read Retinal vs Zinc PCA: which is better for your skin.

Frequently asked questions

Can I use Retinal and Zinc PCA together?

Yes, it is safe. There is no known chemical conflict between Retinal and Zinc PCA, and neither makes the other less effective. They share a goal (acne), so together they reinforce each other.

Which goes first, Retinal or Zinc PCA?

Apply Zinc PCA first, then Retinal. The general rule is thinnest to thickest texture, and lowest pH first.

Should I use Retinal in the morning or at night?

Retinal: best at night. Start at 0.05% two or three nights a week and build up slowly. Buffer with moisturiser if you are sensitive, and wear SPF daily.

Should I use Zinc PCA in the morning or at night?

Zinc PCA: works morning or night. Use once or twice daily. It works best as part of a niacinamide or oil-control serum.

Is Retinal with Zinc PCA safe during pregnancy?

Retinal is generally avoided during pregnancy and breastfeeding. Ask your doctor about safer alternatives such as azelaic acid or bakuchiol.

More free tools