How to use them
Use them in the same routine at night. Apply Zinc PCA first, then Adapalene, moving from thinnest to thickest texture.
- 1CleanseGentle cleanser, pat dry
- 2Zinc PCA1%, wait about 1 minute
- 3Adapalene0.1%
- 4Moisturiserseal everything in
What Adapalene does
A synthetic retinoid built for acne. It unclogs pores and calms the inflammation behind breakouts. It is more stable than retinol, and in India it is sold as a gel (often by prescription).
- Typical strength
- 0.1%
- When
- PM
- Irritation
- Best for
- Oily And Combination skin
Everything that pairs with Adapalene →
What Zinc PCA does
Zinc salts help regulate sebum and have mild anti-inflammatory and antibacterial effects. That is why zinc so often appears next to niacinamide in oil-control serums.
- Typical strength
- 1%
- When
- AM/PM
- Irritation
- Best for
- Oily And Combination skin
Everything that pairs with Zinc PCA →
Trying to choose one? Read Adapalene vs Zinc PCA: which is better for your skin.
Frequently asked questions
Can I use Adapalene and Zinc PCA together?
Yes, it is safe. There is no known chemical conflict between Adapalene and Zinc PCA, and neither makes the other less effective. They share a goal (acne), so together they reinforce each other.
Which goes first, Adapalene or Zinc PCA?
Apply Zinc PCA first, then Adapalene. The general rule is thinnest to thickest texture, and lowest pH first.
Should I use Adapalene in the morning or at night?
Adapalene: best at night. Apply a thin layer to the whole acne-prone area at night, not just on spots. Expect a purge for 4–6 weeks. Use a moisturiser and daily SPF.
Should I use Zinc PCA in the morning or at night?
Zinc PCA: works morning or night. Use once or twice daily. It works best as part of a niacinamide or oil-control serum.
Is Adapalene with Zinc PCA safe during pregnancy?
Adapalene is generally avoided during pregnancy and breastfeeding. Ask your doctor about safer alternatives such as azelaic acid or bakuchiol.