How to use them
Use them in the same routine morning or night. Apply Exosomes first, then Urea, moving from thinnest to thickest texture. Finish with sunscreen in the morning.
- 1CleanseGentle cleanser, pat dry
- 2Exosomesvaries (plant- or stem-cell-derived), wait about 1 minute
- 3Urea5% – 10% (face), up to 40% (feet)
- 4Moisturiserseal everything in
What Exosomes does
Tiny cell-signalling particles, most often derived from plant or stem-cell cultures for cosmetic use. In-clinic exosome treatments (injected or applied after microneedling) have more published evidence than the topical serums sold direct to consumers. Regulatory status varies by country, and topical evidence is still described as early and limited, so treat "regeneration" or anti-ageing claims with caution.
- Typical strength
- varies (plant- or stem-cell-derived)
- When
- AM/PM
- Irritation
- Best for
- Normal, Dry, Combination And Sensitive skin
Everything that pairs with Exosomes →
What Urea does
A natural moisturising factor that pulls water into skin. At 10% and above it also softens rough, flaky patches. It is excellent for very dry skin, keratosis pilaris and cracked heels.
- Typical strength
- 5% – 10% (face), up to 40% (feet)
- When
- AM/PM
- Irritation
- Best for
- Dry, Normal And Sensitive skin
Everything that pairs with Urea →
Trying to choose one? Read Exosomes vs Urea: which is better for your skin.
Frequently asked questions
Can I use Exosomes and Urea together?
Yes, it is safe. There is no known chemical conflict between Exosomes and Urea, and neither makes the other less effective. They share a goal (barrier and texture), so together they reinforce each other.
Which goes first, Exosomes or Urea?
Apply Exosomes first, then Urea. The general rule is thinnest to thickest texture, and lowest pH first.
Should I use Exosomes in the morning or at night?
Exosomes: works morning or night. If using a topical exosome serum, apply after cleansing and before heavier creams. For in-clinic exosome treatments, use only a qualified, licensed practitioner and ask what the exosomes are derived from.
Should I use Urea in the morning or at night?
Urea: works morning or night. Use 5–10% on the face or body daily. Higher strengths can sting on broken or freshly exfoliated skin.
Is Exosomes with Urea safe during pregnancy?
Neither is a known risk in normal cosmetic amounts, but guidance varies for Exosomes. Check with your doctor.