How to use them
Choose one retinoid and use it 2–4 nights a week. Fill the other nights with hydrating and barrier-repair products.
- 1CleanseGentle cleanser, pat dry
- AMRetinal (day 1)then moisturiser and SPF 50
- PMTretinoin (day 2)then moisturiser
What Retinal does
Retinaldehyde is one conversion step closer to retinoic acid than retinol, so it works faster than retinol while usually being gentler than tretinoin. It also has a mild antibacterial effect useful for acne.
- Typical strength
- 0.05% – 0.2%
- When
- PM
- Irritation
- Best for
- Normal, Oily, Combination And Dry skin
Everything that pairs with Retinal →
What Tretinoin does
The prescription-strength retinoid, and the gold standard for acne and photo-ageing, with decades of evidence. It works directly (no conversion needed), so it is stronger and more irritating than retinol or retinal.
- Typical strength
- 0.025% – 0.1% (prescription)
- When
- PM
- Irritation
- Best for
- Oily, Normal And Combination skin
Everything that pairs with Tretinoin →
Trying to choose one? Read Retinal vs Tretinoin: which is better for your skin.
Frequently asked questions
Can I use Retinal and Tretinoin together?
No, keep them apart. Retinal and Tretinoin are both retinoids. Doubling up does not double results. It just doubles the dryness, peeling and irritation. Pick one.
Which goes first, Retinal or Tretinoin?
Apply Retinal first, then Tretinoin. The general rule is thinnest to thickest texture, and lowest pH first. For this pair, though, it is better not to layer them in the same routine at all.
Should I use Retinal in the morning or at night?
Retinal: best at night. Start at 0.05% two or three nights a week and build up slowly. Buffer with moisturiser if you are sensitive, and wear SPF daily.
Should I use Tretinoin in the morning or at night?
Tretinoin: best at night. Use only as prescribed: a pea-sized amount on completely dry skin at night, starting 2–3 nights a week. Expect dryness and a possible purge for 4–8 weeks. Daily SPF is essential.
Is Retinal with Tretinoin safe during pregnancy?
Retinal and Tretinoin is generally avoided during pregnancy and breastfeeding. Ask your doctor about safer alternatives such as azelaic acid or bakuchiol.