How to use them
Use them in the same routine morning or night. Apply PDRN first, then Tea Tree Oil, moving from thinnest to thickest texture. Finish with sunscreen in the morning.
- 1CleanseGentle cleanser, pat dry
- 2PDRNvaries (often with PN/polynucleotides blends), wait about 1 minute
- 3Tea Tree Oil5% (diluted)
- 4Moisturiserseal everything in
What PDRN does
Polydeoxyribonucleotide, a salmon-DNA-derived ingredient best known from in-clinic "salmon DNA" injections and now sold in serums. Early clinical studies suggest it may support tissue repair and hydration, but topical (as opposed to injected) evidence is still limited, so treat claims of dramatic results with caution.
- Typical strength
- varies (often with PN/polynucleotides blends)
- When
- AM/PM
- Irritation
- Best for
- Normal, Dry, Sensitive And Combination skin
Everything that pairs with PDRN →
What Tea Tree Oil does
An essential oil with modest evidence against mild acne. It works more slowly than benzoyl peroxide but causes less dryness. Undiluted it can irritate or sensitise skin, so it belongs in a formulated product.
- Typical strength
- 5% (diluted)
- When
- AM/PM
- Irritation
- Best for
- Oily And Combination skin
Everything that pairs with Tea Tree Oil →
Frequently asked questions
Can I use PDRN and Tea Tree Oil together?
Yes, it is safe. There is no known chemical conflict between PDRN and Tea Tree Oil, and neither makes the other less effective.
Which goes first, PDRN or Tea Tree Oil?
Apply PDRN first, then Tea Tree Oil. The general rule is thinnest to thickest texture, and lowest pH first.
Should I use PDRN in the morning or at night?
PDRN: works morning or night. Use as a serum step, morning or night. It has no known irritancy, so it layers easily with most other actives. It is not a substitute for an in-clinic PDRN treatment, which uses injectable-grade material under medical supervision.
Should I use Tea Tree Oil in the morning or at night?
Tea Tree Oil: works morning or night. Use a product with around 5% tea tree, or dilute it. Never apply the pure oil straight to the face. Patch test first.
Is PDRN with Tea Tree Oil safe during pregnancy?
Neither is a known risk in normal cosmetic amounts, but guidance varies for PDRN and Tea Tree Oil. Check with your doctor.